| 06-Sep-25 | Round 1 | Fylde | 15:00 | Hull Ionians |
| 06-Sep-25 | Hull | 14:00 | Rossendale | |
| 06-Sep-25 | Macclesfield | 15:00 | Sheffield Tigers | |
| 06-Sep-25 | Preston Grasshoppers | 14:30 | Billingham | |
| 06-Sep-25 | Scunthorpe | 15:00 | Darlington Mowden Park | |
| 06-Sep-25 | Sheffield | 15:00 | Otley | |
| 06-Sep-25 | Tynedale | 15:00 | Wharfedale | |
| 13-Sep-25 | Round 2 | Billingham | 14:15 | Wharfedale |
| 13-Sep-25 | Darlington Mowden Park | 15:00 | Tynedale | |
| 13-Sep-25 | Hull Ionians | 15:00 | Hull | |
| 13-Sep-25 | Otley | 15:00 | Scunthorpe | |
| 13-Sep-25 | Preston Grasshoppers | 14:30 | Fylde | |
| 13-Sep-25 | Rossendale | 15:00 | Macclesfield | |
| 13-Sep-25 | Sheffield Tigers | 15:00 | Sheffield | |
| 20-Sep-25 | Round 3 | Fylde | 15:00 | Billingham |
| 20-Sep-25 | Hull | 14:00 | Preston Grasshoppers | |
| 20-Sep-25 | Macclesfield | 15:00 | Hull Ionians | |
| 20-Sep-25 | Scunthorpe | 15:00 | Sheffield Tigers | |
| 20-Sep-25 | Sheffield | 15:00 | Rossendale | |
| 20-Sep-25 | Tynedale | 15:00 | Otley | |
| 20-Sep-25 | Wharfedale | 14:00 | Darlington Mowden Park | |
| 27-Sep-25 | Round 4 | Billingham | 14:15 | Darlington Mowden Park |
| 27-Sep-25 | Fylde | 15:00 | Hull | |
| 27-Sep-25 | Hull Ionians | 15:00 | Sheffield | |
| 27-Sep-25 | Otley | 15:00 | Wharfedale | |
| 27-Sep-25 | Preston Grasshoppers | 14:30 | Macclesfield | |
| 27-Sep-25 | Rossendale | 15:00 | Scunthorpe | |
| 27-Sep-25 | Sheffield Tigers | 15:00 | Tynedale | |
| 04-Oct-25 | Round 5 | Darlington Mowden Park | 15:00 | Otley |
| 04-Oct-25 | Hull | 14:00 | Billingham | |
| 04-Oct-25 | Macclesfield | 15:00 | Fylde | |
| 04-Oct-25 | Scunthorpe | 15:00 | Hull Ionians | |
| 04-Oct-25 | Sheffield | 15:00 | Preston Grasshoppers | |
| 04-Oct-25 | Tynedale | 15:00 | Rossendale | |
| 04-Oct-25 | Wharfedale | 14:00 | Sheffield Tigers | |
| 11-Oct-25 | Round 6 | Billingham | 14:15 | Otley |
| 11-Oct-25 | Fylde | 15:00 | Sheffield | |
| 11-Oct-25 | Hull | 14:00 | Macclesfield | |
| 11-Oct-25 | Hull Ionians | 15:00 | Tynedale | |
| 11-Oct-25 | Preston Grasshoppers | 14:30 | Scunthorpe | |
| 11-Oct-25 | Rossendale | 15:00 | Wharfedale | |
| 11-Oct-25 | Sheffield Tigers | 15:00 | Darlington Mowden Park | |
| 18-Oct-25 | Round 7 | Darlington Mowden Park | 15:00 | Rossendale |
| 18-Oct-25 | Macclesfield | 15:00 | Billingham | |
| 18-Oct-25 | Otley | 15:00 | Sheffield Tigers | |
| 18-Oct-25 | Scunthorpe | 15:00 | Fylde | |
| 18-Oct-25 | Sheffield | 15:00 | Hull | |
| 18-Oct-25 | Tynedale | 15:00 | Preston Grasshoppers | |
| 18-Oct-25 | Wharfedale | 14:00 | Hull Ionians | |
| 25-Oct-25 | Round 8 | Billingham | 14:15 | Sheffield Tigers |
| 25-Oct-25 | Fylde | 15:00 | Tynedale | |
| 25-Oct-25 | Hull | 14:00 | Scunthorpe | |
| 25-Oct-25 | Hull Ionians | 15:00 | Darlington Mowden Park | |
| 25-Oct-25 | Macclesfield | 15:00 | Sheffield | |
| 25-Oct-25 | Preston Grasshoppers | 14:30 | Wharfedale | |
| 25-Oct-25 | Rossendale | 15:00 | Otley | |
| 08-Nov-25 | Round 9 | Darlington Mowden Park | 15:00 | Preston Grasshoppers |
| 08-Nov-25 | Otley | 14:00 | Hull Ionians | |
| 08-Nov-25 | Scunthorpe | 14:00 | Macclesfield | |
| 08-Nov-25 | Sheffield | 14:15 | Billingham | |
| 08-Nov-25 | Sheffield Tigers | 14:00 | Rossendale | |
| 08-Nov-25 | Tynedale | 14:00 | Hull | |
| 08-Nov-25 | Wharfedale | 14:00 | Fylde | |
| 15-Nov-25 | Round 10 | Billingham | 14:15 | Rossendale |
| 15-Nov-25 | Fylde | 15:00 | Darlington Mowden Park | |
| 15-Nov-25 | Hull | 14:00 | Wharfedale | |
| 15-Nov-25 | Hull Ionians | 14:00 | Sheffield Tigers | |
| 15-Nov-25 | Macclesfield | 15:00 | Tynedale | |
| 15-Nov-25 | Preston Grasshoppers | 14:30 | Otley | |
| 15-Nov-25 | Sheffield | 15:00 | Scunthorpe | |
| 22-Nov-25 | Round 11 | Darlington Mowden Park | 15:00 | Hull |
| 22-Nov-25 | Otley | 14:00 | Fylde | |
| 22-Nov-25 | Rossendale | 14:30 | Hull Ionians | |
| 22-Nov-25 | Scunthorpe | 14:00 | Billingham | |
| 22-Nov-25 | Sheffield Tigers | 14:00 | Preston Grasshoppers | |
| 22-Nov-25 | Tynedale | 14:00 | Sheffield | |
| 22-Nov-25 | Wharfedale | 14:00 | Macclesfield | |
| 06-Dec-25 | Round 12 | Billingham | 14:15 | Hull Ionians |
| 06-Dec-25 | Fylde | 15:00 | Sheffield Tigers | |
| 06-Dec-25 | Hull | 14:00 | Otley | |
| 06-Dec-25 | Macclesfield | 15:00 | Darlington Mowden ParkPark | |
| 06-Dec-25 | Preston Grasshoppers | 14:30 | Rossendale | |
| 06-Dec-25 | Scunthorpe | 14:00 | Tynedale | |
| 06-Dec-25 | Sheffield | 14:15 | Wharfedale | |
| 13-Dec-25 | Round 13 | Darlington Mowden Park | 15:00 | Sheffield |
| 13-Dec-25 | Hull Ionians | 14:00 | Preston Grasshoppers | |
| 13-Dec-25 | Otley | 14:00 | Macclesfield | |
| 13-Dec-25 | Rossendale | 14:30 | Fylde | |
| 13-Dec-25 | Sheffield Tigers | 14:00 | Hull | |
| 13-Dec-25 | Tynedale | 14:00 | Billingham | |
| 13-Dec-25 | Wharfedale | 14:00 | Scunthorpe | |
| 20-Dec-25 | Round 14 | Fylde | 15:00 | Preston Grasshoppers |
| 20-Dec-25 | Hull | 14:00 | Hull Ionians | |
| 20-Dec-25 | Macclesfield | 15:00 | Rossendale | |
| 20-Dec-25 | Scunthorpe | 14:00 | Otley | |
| 20-Dec-25 | Sheffield | TBC | Sheffield Tigers | |
| 20-Dec-25 | Tynedale | 14:00 | Darlington Mowden Park | |
| 20-Dec-25 | Wharfedale | 14:00 | Billingham | |
| 10-Jan-26 | Round 15 | Billingham | 14:15 | Fylde |
| 10-Jan-26 | Darlington Mowden Park | 15:00 | Wharfedale | |
| 10-Jan-26 | Hull Ionians | 14:00 | Macclesfield | |
| 10-Jan-26 | Otley | 14:00 | Tynedale | |
| 10-Jan-26 | Preston Grasshoppers | 14:30 | Hull | |
| 10-Jan-26 | Rossendale | 14:30 | Sheffield | |
| 10-Jan-26 | Sheffield Tigers | 14:00 | Scunthorpe | |
| 17-Jan-26 | Round 16 | Darlington Mowden Park | 15:00 | Billingham |
| 17-Jan-26 | Hull | 14:00 | Fylde | |
| 17-Jan-26 | Macclesfield | 15:00 | Preston Grasshoppers | |
| 17-Jan-26 | Scunthorpe | 14:00 | Rossendale | |
| 17-Jan-26 | Sheffield | 15:00 | Hull Ionians | |
| 17-Jan-26 | Tynedale | 14:00 | Sheffield Tigers | |
| 17-Jan-26 | Wharfedale | 14:00 | Otley | |
| 24-Jan-26 | Round 17 | Billingham | 14:15 | Hull |
| 24-Jan-26 | Fylde | 15:00 | Macclesfield | |
| 24-Jan-26 | Hull Ionians | 14:00 | Scunthorpe | |
| 24-Jan-26 | Otley | 14:00 | Darlington Mowden Park | |
| 24-Jan-26 | Preston Grasshoppers | 14:30 | Sheffield | |
| 24-Jan-26 | Rossendale | 14:30 | Tynedale | |
| 24-Jan-26 | Sheffield Tigers | 14:00 | Wharfedale | |
| 31-Jan-26 | Round 18 | Darlington Mowden Park | 15:00 | Sheffield Tigers |
| 31-Jan-26 | Macclesfield | 15:00 | Hull | |
| 31-Jan-26 | Otley | 14:00 | Billingham | |
| 31-Jan-26 | Scunthorpe | 14:00 | Preston Grasshoppers | |
| 31-Jan-26 | Sheffield | 15:00 | Fylde | |
| 31-Jan-26 | Tynedale | 14:00 | Hull Ionians | |
| 31-Jan-26 | Wharfedale | 14:00 | Rossendale | |
| 14-Feb-26 | Round 19 | Billingham | 14:15 | Macclesfield |
| 14-Feb-26 | Fylde | 15:00 | Scunthorpe | |
| 14-Feb-26 | Hull | 14:00 | Sheffield | |
| 14-Feb-26 | Hull Ionians | 14:00 | Wharfedale | |
| 14-Feb-26 | Preston Grasshoppers | 14:30 | Tynedale | |
| 14-Feb-26 | Rossendale | 14:30 | Darlington Mowden Park | |
| 14-Feb-26 | Sheffield Tigers | 14:00 | Otley | |
| 21-Feb-26 | Round 20 | Darlington Mowden Park | 15:00 | Hull Ionians |
| 21-Feb-26 | Otley | 14:00 | Rossendale | |
| 21-Feb-26 | Scunthorpe | 14:00 | Hull | |
| 21-Feb-26 | Sheffield | 15:00 | Macclesfield | |
| 21-Feb-26 | Sheffield Tigers | 14:00 | Billingham | |
| 21-Feb-26 | Tynedale | 14:00 | Fylde | |
| 21-Feb-26 | Wharfedale | 14:00 | Preston Grasshoppers | |
| 28-Feb-26 | Round 21 | Billingham | 14:15 | Sheffield |
| 28-Feb-26 | Fylde | 15:00 | Wharfedale | |
| 28-Feb-26 | Hull | 14:00 | Tynedale | |
| 28-Feb-26 | Hull Ionians | 14:00 | Otley | |
| 28-Feb-26 | Macclesfield | 15:00 | Scunthorpe | |
| 28-Feb-26 | Preston Grasshoppers | 14:30 | Darlington Mowden Park | |
| 28-Feb-26 | Rossendale | 14:30 | Sheffield Tigers | |
| 14-Mar-26 | Round 22 | Darlington Mowden Park | 15:00 | Fylde |
| 14-Mar-26 | Otley | 15:00 | Preston Grasshoppers | |
| 14-Mar-26 | Rossendale | 15:00 | Billingham | |
| 14-Mar-26 | Scunthorpe | 15:00 | Sheffield | |
| 14-Mar-26 | Sheffield Tigers | 15:00 | Hull Ionians | |
| 14-Mar-26 | Tynedale | 15:00 | Macclesfield | |
| 14-Mar-26 | Wharfedale | 14:00 | Hull | |
| 21-Mar-26 | Round 23 | Billingham | 14:15 | Scunthorpe |
| 21-Mar-26 | Fylde | 15:00 | Otley | |
| 21-Mar-26 | Hull | 14:00 | Darlington Mowden Park | |
| 21-Mar-26 | Hull Ionians | 15:00 | Rossendale | |
| 21-Mar-26 | Macclesfield | 15:00 | Wharfedale | |
| 21-Mar-26 | Preston Grasshoppers | 14:30 | Sheffield Tigers | |
| 21-Mar-26 | Sheffield | 15:00 | Tynedale | |
| 11-Apr-26 | Round 24 | Darlington Mowden Park | 15:00 | Macclesfield |
| 11-Apr-26 | Hull Ionians | 15:00 | Billingham | |
| 11-Apr-26 | Otley | 15:00 | Hull | |
| 11-Apr-26 | Rossendale | 15:00 | Preston Grasshoppers | |
| 11-Apr-26 | Sheffield Tigers | 15:00 | Fylde | |
| 11-Apr-26 | Tynedale | 15:00 | Scunthorpe | |
| 11-Apr-26 | Wharfedale | 14:00 | Sheffield | |
| 18-Apr-26 | Round 25 | Billingham | 14:15 | Tynedale |
| 18-Apr-26 | Fylde | 15:00 | Rossendale | |
| 18-Apr-26 | Hull | 14:00 | Sheffield Tigers | |
| 18-Apr-26 | Macclesfield | 15:00 | Otley | |
| 18-Apr-26 | Preston Grasshoppers | 14:30 | Hull Ionians | |
| 18-Apr-26 | Scunthorpe | 15:00 | Wharfedale | |
| 18-Apr-26 | Sheffield | 15:00 | Darlington Mowden Park | |
| 25-Apr-26 | Round 26 | Billingham | 15:00 | Preston Grasshoppers |
| 25-Apr-26 | Darlington Mowden Park | 15:00 | Scunthorpe | |
| 25-Apr-26 | Hull Ionians | 15:00 | Fylde | |
| 25-Apr-26 | Otley | 15:00 | Sheffield | |
| 25-Apr-26 | Rossendale | 15:00 | Hull | |
| 25-Apr-26 | Sheffield Tigers | 15:00 | Macclesfield | |
| 25-Apr-26 | Wharfedale | 15:00 | Tynedale |